We present a novel dynamic programming framework that allows one to compute tight upper bounds for the p-values of gapped local alignments in pseudo–polynomial time. Our algorith...
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Abstract. Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present e...
Comparative analysis of biomolecular networks constructed using measurements from different conditions, tissues, and organisms offer a powerful approach to understanding the stru...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. ...