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    ALMOB
    2008
    127views more  ALMOB 2008»
    HuMiTar: A sequence-based method for prediction of human microRNA targets
    13 years 11 months ago
    HuMiTar: A sequence-based method for prediction of human microRNA targets
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    Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
    Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
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    ALMOB
    2008
    92views more  ALMOB 2008»
    Reconstructing phylogenies from noisy quartets in polynomial time with a high success probability
    13 years 11 months ago
    Reconstructing phylogenies from noisy quartets in polynomial time with a high success probability
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    Background: In recent years, quartet-based phylogeny reconstruction methods have received considerable attentions in the computational biology community. Traditionally, the accura...
    Gang Wu, Ming-Yang Kao, Guohui Lin, Jia-Huai You
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    ALMOB
    2008
    160views more  ALMOB 2008»
    Syntenator: Multiple gene order alignments with a gene-specific scoring function
    13 years 11 months ago
    Syntenator: Multiple gene order alignments with a gene-specific scoring function
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    Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
    Christian Rödelsperger, Christoph Dieterich
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    ALMOB
    2008
    93views more  ALMOB 2008»
    A weighted average difference method for detecting differentially expressed genes from microarray data
    13 years 11 months ago
    A weighted average difference method for detecting differentially expressed genes from microarray data
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    Background: Identification of differentially expressed genes (DEGs) under different experimental conditions is an important task in many microarray studies. However, choosing whic...
    Koji Kadota, Yuji Nakai, Kentaro Shimizu
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    ALMOB
    2008
    69views more  ALMOB 2008»
    Learning from positive examples when the negative class is undetermined- microRNA gene identification
    13 years 11 months ago
    Learning from positive examples when the negative class is undetermined- microRNA gene identification
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    Background: The application of machine learning to classification problems that depend only on positive examples is gaining attention in the computational biology community. We an...
    Malik Yousef, Segun Jung, Louise C. Showe, Michael...
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    ALMOB
    2008
    124views more  ALMOB 2008»
    A scoring matrix approach to detecting miRNA target sites
    13 years 11 months ago
    A scoring matrix approach to detecting miRNA target sites
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    Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
    Simon Moxon, Vincent Moulton, Jan T. Kim
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    ALMOB
    2008
    43views more  ALMOB 2008»
    On the optimality of the neighbor-joining algorithm
    13 years 11 months ago
    On the optimality of the neighbor-joining algorithm
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    Kord Eickmeyer, Peter Huggins, Lior Pachter, Rurik...
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    ALMOB
    2008
    95views more  ALMOB 2008»
    A stitch in time: Efficient computation of genomic DNA melting bubbles
    13 years 11 months ago
    A stitch in time: Efficient computation of genomic DNA melting bubbles
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    Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
    Eivind Tøstesen
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    ALMOB
    2008
    112views more  ALMOB 2008»
    Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
    13 years 11 months ago
    Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
    Download  www.almob.org
    Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
    Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
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    ALMOB
    2008
    82views more  ALMOB 2008»
    Protein sequence and structure alignments within one framework
    13 years 11 months ago
    Protein sequence and structure alignments within one framework
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    Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
    Gundolf Schenk, Thomas Margraf, Andrew E. Torda
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