Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays...
—Microarray technology has provided an opportunity to simultaneously monitor the expression levels of a large number of genes in response to intentional perturbations. A necessar...