The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
One of the major problems in biological data integration is that many data sources are stored as flat-files, with a variety of different layouts. Integrating data from such sour...
Kaushik Sinha, Xuan Zhang, Ruoming Jin, Gagan Agra...
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
We introduce a new ensemble method based on decision tree to discover significant and diversified rules for subtype classification of childhood acute lymphoblastic leukemia, a ...
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...