We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Protein-protein interaction plays critical roles in cellular functions. In this work, we propose a computational method to predict protein-protein interaction by using support vec...
Cytoplasmic post-transcriptional modification of mRNA transcripts in the form of polyadenylated (poly(A)) tails plays a key role in their translational control. The timing and degr...
Eric C. Rouchka, Xiangping Wang, James H. Graham, ...
Protein phosphorylation is a crucial regulatory mechanism in various organisms. With recent improvements in mass spectrometry, phosphorylation site data are rapidly accumulating. D...
Jianjiong Gao, Ganesh Kumar Agrawal, Jay J. Thelen...
Several applications require the joint display of two phylogenetic trees whose leaves are matched by inter-tree edges. This issue arises, for example, when comparing gene trees and...
Mukul S. Bansal, Wen-Chieh Chang 0002, Oliver Eule...
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...
Here we present a simple method based on graph spectral properties to automatically partition multi-domain proteins into individual domains. The identification of structural domain...
Association analysis is one of the most popular analysis paradigms in data mining. Despite the solid foundation of association analysis and its potential applications, this group o...
Gowtham Atluri, Rohit Gupta, Gang Fang, Gaurav Pan...