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BICOB
2010
Springer
13 years 9 months ago
Multiple Kernel Learning for Fold Recognition
Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
Huzefa Rangwala
BICOB
2010
Springer
13 years 10 months ago
Iterative Split Adjustment for Building Multilabel Decision Trees
A decision tree induction method for multilabel classification tasks (IS-MLT) is presented which uses an iterative approach for determining the best split at each node. The propo...
Aiyesha Ma, Ishwar K. Sethi
BICOB
2010
Springer
13 years 11 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
BICOB
2010
Springer
14 years 4 months ago
A Grid-Enabled Problem Solving Environment for QTL Analysis in R
We present a grid-enabled problem solving environment (PSE), for multidimensional QTL analysis. The concept of a computational grid has not been fully realized within this and oth...
Mahen Jayawardena, Carl Nettelblad, Salman Zubair ...
BICOB
2010
Springer
14 years 4 months ago
Algebraic Theory of DNA Recombination
In this paper we investigate the structure and representation of n-ary algebras arising from DNA recombination, where n is a number of DNA segments participating in recombination. ...
Sergei R. Sverchkov
BICOB
2010
Springer
14 years 4 months ago
Folding-aware and Structure-conscious 3D Substructures in Folding Data: Identification and Applications
Molecular dynamics simulations have been employed by biologists to study the protein folding problem. Such simulations have resulted in a large number of protein folding trajector...
Hui Yang, Saurabh Gupte, Runtang Wang, Rahul Parte
BICOB
2010
Springer
14 years 4 months ago
On Building a Quantitative Food-Disease-Gene Network
Hui Yang, Abhishek Sharma, Rajesh Swaminathan, Vil...
BICOB
2010
Springer
14 years 4 months ago
Biological Relevance Detection via Network Dynamic Analysis
Most existing approaches for gene selection are based on evaluating the statistical relevance. However, there are remarkable discrepancies between statistical relevance and biolog...
Zheng Zhao, Huan Liu, Jiangxin Wang, Yung Chang