Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
The analysis and interpretation of relationships between biological molecules, networks and concepts is becoming a major bottleneck in systems biology. Very often the pure amount ...
Georgios A. Pavlopoulos, Anna-Lynn Wegener, Reinha...
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Background: In computer science, database systems are based on the relational model founded by Edgar Codd in 1970. On the other hand, in the area of biology the word 'databas...
Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
Background: Analysis of a microarray experiment often results in a list of hundreds of diseaseassociated genes. In order to suggest common biological processes and functions for t...
Evolutionary search algorithms have become an essential asset in the algorithmic toolbox for solving high-dimensional optimization problems in across a broad range of bioinformati...
This editorial introduces BioData Mining, a new journal which publishes research articles related to advances in computational methods and techniques for the extraction of useful ...
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...