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BIRD
2007
Springer
107views Bioinformatics» more  BIRD 2007»
14 years 5 months ago
Prediction of Structurally-Determined Coiled-Coil Domains with Hidden Markov Models
The coiled-coil protein domain is a widespread structural motif known to be involved in a wealth of key interactions in cells and organisms. Coiled-coil recognition and prediction ...
Piero Fariselli, Daniele Molinini, Rita Casadio, A...
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 6 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
BIBM
2007
IEEE
14 years 6 months ago
A Semi-supervised Learning Approach to Disease Gene Prediction
Discovering human disease-causing genes (disease genes in short) is one of the most challenging problems in bioinformatics and biomedicine, as most diseases are related in some wa...
Thanh Phuong Nguyen, Tu Bao Ho
BIBM
2007
IEEE
135views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
Graph Kernel-Based Learning for Gene Function Prediction from Gene Interaction Network
Prediction of gene functions is a major challenge to biologists in the post-genomic era. Interactions between genes and their products compose networks and can be used to infer ge...
Xin Li, Zhu Zhang, Hsinchun Chen, Jiexun Li
BIBM
2007
IEEE
137views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
A Multi-metric Similarity Based Analysis of Microarray Data
Clustering has been shown to be effective in analyzing functional relationships of genes. However, no single clustering method with single distance metric is capable of capturing ...
Fatih Altiparmak, Selnur Erdal, Ozgur Ozturk, Haka...
BIBM
2007
IEEE
101views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
Improved Methods for Template-Matching in Electron-Density Maps Using Spherical Harmonics
An important problem in high-throughput protein crystallography is constructing a protein model from an electron-density map. Previous work by some of this paper’s authors [1] d...
Frank DiMaio, Ameet Soni, George N. Phillips, Jude...
BIBM
2007
IEEE
144views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
Kinetic Modeling Using BioPAX Ontology
Thousands of biochemical interactions are available for download from curated databases such as Reactome, Pathway Interaction Database and other sources in the Biological Pathways...
Oliver Ruebenacker, Ion I. Moraru, James C. Schaff...
BIBM
2007
IEEE
162views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
Multiple Interacting Subcellular Structure Tracking by Sequential Monte Carlo Method
With the wide application of green fluorescent protein (GFP) in the study of live cells, there is a surging need for the computer-aided analysis on the huge amount of image seque...
Quan Wen, Jean Gao, Kate Luby-Phelps
BIBM
2007
IEEE
126views Bioinformatics» more  BIBM 2007»
14 years 6 months ago
Microarray Image Denoising Using a Two-Stage Multiresolution Technique
DNA microarrays have demonstrated an excellent potential in correlating specific gene expression profiles to specific conditions. However, they are affected by inherent noise. ...
Hara Stefanou, Thanasis Margaritis, Dimitris Kafet...