Background: Clustering is a popular data exploration technique widely used in microarray data analysis. Most conventional clustering algorithms, however, generate only one set of ...
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Background: Biological knowledge is represented in scientific literature that often describes the function of genes/ proteins (bioentities) in terms of their interactions (biointe...
Adriano Barbosa-Silva, Theodoros G. Soldatos, Ivan...
Background: The analysis and usage of biological data is hindered by the spread of information across multiple repositories and the difficulties posed by different nomenclature sy...
Javier Garcia-Garcia, Emre Guney, Ramon Aragues, J...
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
The analysis and interpretation of relationships between biological molecules, networks and concepts is becoming a major bottleneck in systems biology. Very often the pure amount ...
Georgios A. Pavlopoulos, Anna-Lynn Wegener, Reinha...
Modeling molecular interactions in biological networks is important from various perspectives such as predicting side effects of drugs, explaining unusual cellular behavior and dr...
Bioinformaticians are accustomed to going through analysis steps, in which they employ several data sources, like protein sequence and protein interaction databases, to carry out t...
Farzad Kohantorabi, Gregory Butler, Christopher J....
: Understanding complex biological systems requires data from manifold biological levels. Often this data is analysed in some meaningful context, for example, by integrating it int...