Exact matching of single patterns in DNA and amino acid sequences is studied. We performed an extensive experimental comparison of algorithms presented in the literature. In additi...
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Abstract. We describe a new method for the exploration of evolutionary relations between protein structures. The approach is based on the ESSM algorithm for detecting structural mu...
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
The swap matching problem consists if finding a pattern in a text, while allowing for transpositions in the pattern. A new approach using a graph-theoretic model was presented in [...
Pavlos Antoniou, Costas S. Iliopoulos, Inuka Jayas...
Abstract. Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many pro...
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
We introduce a new type of workflow design system called e-BioFlow and illustrate it by means of a simple sequence alignment workflow. E-BioFlow, intended to model advanced scienti...
Ingo H. C. Wassink, Han Rauwerda, Paul E. van der ...