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BIRD
2008
Springer
177views Bioinformatics» more  BIRD 2008»
14 years 8 days ago
GENFOCS - A Comparative Tool on Gene Finding with Sensitivity and Specificity
  The  latest  developments  in  DNA  sequencing  tech­  niques paved the way for tremendous increase in bio­  logical databases. Once the whole DNA sequen...
M. A. Lijo Anto, G. Gopakumar, Achuthsankar S. Nai...
BIRD
2008
Springer
221views Bioinformatics» more  BIRD 2008»
14 years 29 days ago
Comparison of Exact String Matching Algorithms for Biological Sequences
Exact matching of single patterns in DNA and amino acid sequences is studied. We performed an extensive experimental comparison of algorithms presented in the literature. In additi...
Petri Kalsi, Hannu Peltola, Jorma Tarhio
BIRD
2008
Springer
109views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
A Robust Class of Stable Proteins in the 2D HPC Model
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
Alireza Hadj Khodabakhshi, Ján Manuch, Aras...
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
BIRD
2008
Springer
159views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
Exploration of Evolutionary Relations between Protein Structures
Abstract. We describe a new method for the exploration of evolutionary relations between protein structures. The approach is based on the ESSM algorithm for detecting structural mu...
Natalja Kurbatova, Juris Viksna
BIRD
2008
Springer
14 years 1 months ago
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
Ulrike Mückstein, Hakim Tafer, Stephan H. F. ...
BIRD
2008
Springer
119views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
Implementation of a Swap Matching Algorithm Using a Graph Theoretic Model
The swap matching problem consists if finding a pattern in a text, while allowing for transpositions in the pattern. A new approach using a graph-theoretic model was presented in [...
Pavlos Antoniou, Costas S. Iliopoulos, Inuka Jayas...
BIRD
2008
Springer
163views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
Multi-functional Protein Clustering in PPI Networks
Abstract. Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many pro...
Clara Pizzuti, Simona E. Rombo
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
BIRD
2008
Springer
123views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
E-BioFlow: Different Perspectives on Scientific Workflows
We introduce a new type of workflow design system called e-BioFlow and illustrate it by means of a simple sequence alignment workflow. E-BioFlow, intended to model advanced scienti...
Ingo H. C. Wassink, Han Rauwerda, Paul E. van der ...