BMCBI
2010
13 years 11 months ago
2010
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
BMCBI
2010
13 years 11 months ago
2010
Background: Text mining has become a useful tool for biologists trying to understand the genetics of diseases. In particular, it can help identify the most interesting candidate g...
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
BMCBI
2010
13 years 11 months ago
2010
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
BMCBI
2010
13 years 11 months ago
2010
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
BMCBI
2010
13 years 11 months ago
2010
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
BMCBI
2010
13 years 11 months ago
2010
Background: Likelihood (ML)-based phylogenetic inference has become a popular method for estimating the evolutionary relationships among species based on genomic sequence data. Th...
BMCBI
2010
13 years 11 months ago
2010
Background: In recent years, Data Mining technology has been applied more than ever before in the field of traditional Chinese medicine (TCM) to discover regularities from the exp...
BMCBI
2010
13 years 11 months ago
2010
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...