Given an assembled genome of a diploid organism the haplotype assembly problem can be formulated as retrieval of a pair of haplotypes from a set of aligned weighted SNP fragments....
We propose an algorithm of global multiple sequence alignment that is based on a measure of what we call information discrepancy. The algorithm follows a progressive alignment ite...
Min Zhang, Weiwu Fang, Junhua Zhang, Zhongxian Chi
The task of the quartet puzzling problem is to find a best-fitting binary X-tree for a finite n-set from confidence values for the 3 n 4 binary trees with exactly four leaves from...
Jan Weyer-Menkhoff, Claudine Devauchelle, Alexande...
A DNA microarray can track the expression levels of thousands of genes simultaneously. Previous research has demonstrated that this technology can be useful in the classification ...
Yu Wang 0008, Igor V. Tetko, Mark A. Hall, Eibe Fr...
High throughput virtual screening is acknowledged as the initial means for identifying hit compounds that will be eventually transformed to leads or drug candidates. To improve qu...
Suzanne W. Sirois, George Hatzakis, Dongqing Wei, ...
We introduce a new family of metrics for graphs of fixed size, based on counting-independent sets. Our definition is simpler and easier to e than the edge ideal metric family defi...
Microarrays are becoming a ubiquitous tool of research in life sciences. However, the working principles of microarray-based methodologies are often misunderstood or apparently ig...
Alessandra Riva, Anne-Sophie Carpentier, Bruno Tor...
Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can ...
Izabela Makalowska, Chiao-Feng Lin, Wojciech Makal...