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BMCBI
2011
13 years 6 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...
BMCBI
2010
87views more  BMCBI 2010»
13 years 6 months ago
A fast and robust hepatocyte quantification algorithm including vein processing
Background: Quantification of different types of cells is often needed for analysis of histological images. In our project, we compute the relative number of proliferating hepatoc...
Tetyana Ivanovska, Andrea Schenk, André Hom...
BMCBI
2006
87views more  BMCBI 2006»
13 years 12 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2010
97views more  BMCBI 2010»
13 years 12 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...