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CIBCB
2006
IEEE
14 years 3 months ago
E2D: A Novel Tool for Annotating Protein Domains in Expressed Sequence Tags
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
Guo-Hsing Lee, Nai-Yu Chuang, Wen-Dar Lin, Chung-D...
CIBCB
2006
IEEE
14 years 3 months ago
Machine Learning in Basecalling Decoding Trace Peak Behaviour
— DNA sequence basecalling is commonly regarded as a solved problem, despite significant error rates being reflected in inaccuracies in databases and genome annotations. These er...
David Thornley, Stavros Petridis
CIBCB
2006
IEEE
14 years 3 months ago
A Model-Free Greedy Gene Selection for Microarray Sample Class Prediction
— Microarray data analysis is notoriously challenging as it involves a huge number of genes compared to only a limited number of samples. Gene selection, to detect the most signi...
Yi Shi, Zhipeng Cai, Lizhe Xu, Wei Ren, Randy Goeb...
CIBCB
2006
IEEE
14 years 3 months ago
Motif Evaluation by Leave-one-out Scoring
Abstract— We propose a new method for collecting information on regulatory elements found by any motif discovery program. We suggest that combining the results of n leave-oneout ...
Audrey Girouard, Noah W. Smith, Donna K. Slonim
CIBCB
2006
IEEE
14 years 3 months ago
A Novel Graphical Model Approach to Segmenting Cell Images
— Successful biological image analysis usually requires satisfactory segmentations to identify regions of interest as an intermediate step. Here we present a novel graphical mode...
Shann-Ching Chen, Ting Zhao, Geoffrey J. Gordon, R...
CIBCB
2006
IEEE
14 years 3 months ago
Aggregating Homologous Protein Families in Evolutionary Reconstructions of Herpesviruses
Abstract–Protein families can be used to reconstruct evolutionary histories of organisms. The accuracy of protein assignment to such families is critical for the success of such ...
Boris Mirkin, Renata da Silva Camargo, Trevor I. F...