The concept of a network motif--a small set of interacting genes which produce a predictable behaviour at the network level--has attracted considerable attention amongst network an...
— We introduce a graph-based relational learning approach using graph-rewriting rules for temporal and structural analysis of biological networks changing over time. The analysis...
Functional RNAs (fRNAs) play a key role in gene regulation, at both the transcriptional and translational levels. Identification of fRNA genes can be difficult, given that some cla...
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
— Molecular docking is an essential tool for drug design. It helps the scientist to rapidly know if two molecules, respectively called ligand and receptor, can be combined togeth...
sequence content at an abstract level and offers novel ways to examine the information contained in them. Our approach is an information theoretic search process which uses patter...
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...