CMSB
2009
Springer
14 years 3 months ago
2009
Springer
In this paper we consider the modeling of a selected portion of signal transduction events involved in the angiogenesis process. The detailed model of this process contains a large...
CMSB
2009
Springer
14 years 3 months ago
2009
Springer
Abstract. Elevated temperatures cause proteins in living cells to misfold. They start forming larger and larger aggregates that can eventually lead to the cell's death. The he...
CMSB
2009
Springer
14 years 4 months ago
2009
Springer
Abstract. In systems biology, the number of models of cellular processes increases rapidly, but re-using models in different contexts or for different questions remains a challengi...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
Bio-PEPA is a process algebra for modelling biological systems. An important aspect of Bio-PEPA is the ability it provides to discretise concentrations resulting in a smaller, more...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
A major challenge in computational systems biology is the articulation of a biological process in a form which can be understood by the biologist yet is amenable to computational e...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time st...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
Abstract. In this paper we describe reachability computation for continuous and hybrid systems and its potential contribution to the process of building and debugging biological mo...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
CMSB
2009
Springer
14 years 7 months ago
2009
Springer
Dynamic compartments with mutable configurations and variable volumes are of basic interest for the stochastic modeling of biochemistry in cells. We propose a new language to expr...