COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
Flux coupling analysis is a method to identify blocked and coupled reactions in a metabolic network at steady state. We present a new approach to flux coupling analysis, which uses...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
We present a method for simultaneous dimension reduction and metastability analysis of high dimensional time series. The approach is based on the combination of hidden Markov model...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
. OSCAR3 is an open extensible system for the automated annotation of chemistry in scientific articles, which can process thousands of articles per hour. This XML annotation suppor...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
Abstract. Molecular shapes play an important role in molecular interactions, e.g., between a protein and a ligand. The `outer' shape of a molecule can be approximated by its s...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
The ability to locate promoters within a section of DNA is known to be a very difficult and very important task in DNA analysis. We document an approach that incorporates the conce...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
Abstract. We present an improved adaptive approach for studying systems of ODEs affected by parameter variability and state space uncertainty. Our approach is based on a reformulat...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
Abstract. This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes different...
COMPLIFE
2006
Springer
13 years 11 months ago
2006
Springer
A powerful new software concept to physiologically based pharmacokinetic (PBPK) modelling of drug disposition is presented. It links the inherent modular understanding in pharmacol...