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BMCBI
2005
100views more  BMCBI 2005»
13 years 11 months ago
Speeding disease gene discovery by sequence based candidate prioritization
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
Euan A. Adie, Richard R. Adams, Kathryn L. Evans, ...
BMCBI
2010
115views more  BMCBI 2010»
13 years 11 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BIBM
2007
IEEE
14 years 5 months ago
A Semi-supervised Learning Approach to Disease Gene Prediction
Discovering human disease-causing genes (disease genes in short) is one of the most challenging problems in bioinformatics and biomedicine, as most diseases are related in some wa...
Thanh Phuong Nguyen, Tu Bao Ho