Rule-based modelling is particularly effective for handling the highly combinatorial aspects of cellular signalling. The dynamics is described in terms of interactions between part...
In this work we develop a new technique for over-approximating (in the sense of timed trace inclusion) continuous dynamical systems by timed auThis technique refines commonly-used ...
We introduce bounded asynchrony, a notion of concurrency tailored to the modeling of biological cell-cell interactions. Bounded asynchrony is the result of a scheduler that bounds ...
Jasmin Fisher, Thomas A. Henzinger, Maria Mateescu...
Abstract. Natural systems, such as organs and organisms, are largescale complex systems with numerous elements and interactions. Modeling such systems can lead to better understand...
Petri nets are a widely used formalism to qualitatively model concurrent systems such as a biological cell. We present techniques for modelling biological processes as Petri nets f...
Elzbieta Krepska, Nicola Bonzanni, K. Anton Feenst...
Abstract. This paper reports on the multi-scale modelling of an intestinal crypt cellular structure coupled with Wnt signalling. Using formal modelling techniques based on the stoc...