: Markov models have been proposed for the classification of DNA-motifs using generative approaches for parameter learning. Here, we propose to apply the discriminative paradigm fo...
Jan Grau, Jens Keilwagen, Alexander E. Kel, Ivo Gr...
Biological systems have to react to environmental and/or developmental changes by adjusting their biochemical/cellular machinery on numerous levels. In many cases small molecules ...
Lothar Willmitzer, Camila Caldana, Alisdair R. Fer...
Since the advent of public data repositories for proteomics data, readily accessible results from high-throughput experiments have been accumulating steadily. Several large-scale p...
Sebastian Klie, Lennart Martens, Juan Antonio Vizc...
: There are several models for the evolutionary process forming a species tree. We examine the Birth-and-Death model (BDM), the Proportional-to-Distinguishable Arrangements (PDA) m...
The most parsimonous distances calculated in pairwise gene order comparisons cannot accurately reflect the true number of events separating two species, unless the number of chan...
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...