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GCB
2010
Springer
122views Biometrics» more  GCB 2010»
13 years 9 months ago
Quantitative Comparison of Genomic-Wide Protein Domain Distributions
Abstract: Investigations into the origins and evolution of regulatory mechanisms require quantitative estimates of the abundance and co-occurrence of functional protein domains amo...
Arli A. Parikesit, Peter F. Stadler, Sonja J. Proh...
GCB
2010
Springer
204views Biometrics» more  GCB 2010»
13 years 9 months ago
Learning Pathway-based Decision Rules to Classify Microarray Cancer Samples
: Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninfor...
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasn...
GCB
2010
Springer
145views Biometrics» more  GCB 2010»
13 years 9 months ago
Shape-based Barrier Estimation for RNAs
: The ability of some RNA molecules to switch between different metastable conformations plays an important role in cellular processes. In order to identify such molecules and to p...
Sergiy Bogomolov, Martin Mann, Björn Voß...
GCB
2010
Springer
198views Biometrics» more  GCB 2010»
13 years 9 months ago
RNALfoldz: Efficient Prediction of Thermodynamically Stable, Local Secondary Structures
Abstract: The search for local RNA secondary structures and the annotation of unusually stable folding regions in genomic sequences are two well motivated bioinformatic problems. I...
Andreas R. Gruber, Stephan H. F. Bernhart, You Zho...
GCB
2010
Springer
182views Biometrics» more  GCB 2010»
13 years 9 months ago
Repeat-aware Comparative Genome Assembly
: The current high-throughput sequencing technologies produce gigabytes of data even when prokaryotic genomes are processed. In a subsequent assembly phase, the generated overlappi...
Peter Husemann, Jens Stoye