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CIBCB
2007
IEEE
13 years 10 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
EPIA
2007
Springer
14 years 2 months ago
Evaluating Simulated Annealing Algorithms in the Optimization of Bacterial Strains
Abstract. In this work, a Simulated Annealing (SA) algorithm is proposed for a Metabolic Engineering task: the optimization of the set of gene deletions to apply to a microbial str...
Miguel Rocha, Rui Mendes, Paulo Maia, José ...