Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Currently, the genome sequencing community is producing shotgun sequence data at a very high rate, but genome finishing is not keeping pace, even with the help from several automa...
Abstract. We study a parametrized definition of gene clusters that permits control over the trade-off between increasing gene content versus conserving gene order within a cluster....
Background: The ability to rapidly map millions of oligonucleotide fragments to a reference genome is crucial to many high throughput genomic technologies. Results: We propose an ...
Wei Li, Jason S. Carroll, Myles Brown, X. Shirley ...
A genomic computing network is a variant of a neural network for which a genome encodes all aspects, both structural and functional, of the network. The genome is evolved by a gen...
David J. Montana, Eric Van Wyk, Marshall Brinn, Jo...
As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome ev...
Mark Marron, Krister M. Swenson, Bernard M. E. Mor...
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
We have been developing a system for comparing multiple genomes, PLATCOM, where users can choose genomes of their choice freely and perform analysis of the selected genomes with a...
Kwangmin Choi, Jeong-Hyeon Choi, Amit Saple, Zhipi...
Genome comparison and analysis can reveal the structures and functions of genome sequences of different species. As more genomes are sequenced, genomic data sources are rapidly in...
Yudong Sun, Anil Wipat, Matthew R. Pocock, P. A. L...
Comparative genomics has become an essential approach for identifying homologous gene candidates and their functions, and for studying genome evolution. We developed GenomeBlast, ...
Guoqing Lu, Liying Jiang, Resa M. Kotalik, Thaine ...