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JCB
2006
123views more  JCB 2006»
13 years 11 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
CSB
2004
IEEE
158views Bioinformatics» more  CSB 2004»
14 years 3 months ago
Algorithms for Association Study Design Using a Generalized Model of Haplotype Conservation
There is considerable interest in computational methods to assist in the use of genetic polymorphism data for locating disease-related genes. Haplotypes, contiguous sets of correl...
Russell Schwartz
WILF
2007
Springer
127views Fuzzy Logic» more  WILF 2007»
14 years 5 months ago
Unsupervised Haplotype Reconstruction and LD Blocks Discovery in a Hidden Markov Framework
In the last years haplotype reconstruction and haplotype blocks discovery, i.e., the estimation of patterns of linkage disequilibrium (LD) in the haplotypes, riveted the attention ...
Alessandro Perina, Marco Cristani, Giovanni Malerb...