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BMCBI
2010
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13 years 11 months ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
WABI
2001
Springer
112views Bioinformatics» more  WABI 2001»
14 years 3 months ago
Finding an Optimal Inversion Median: Experimental Results
We derive a branch-and-bound algorithm to find an optimal inversion median of three signed permutations. The algorithm prunes to manageable size an extremely large search tree usi...
Adam C. Siepel, Bernard M. E. Moret