Sciweavers

ISMB
1997
14 years 24 days ago
Selecting Optimal Oligonucleotide Primers for Multiplex PCR
Weinvestigate the problemof designingefficient multiplex PCRfor medical applications. Weshowthat the problemis NP-completeby transformation to the Multiple Choice Matchingproblema...
Pierre Nicodème, Jean-Marc Steyaert
ISMB
1997
14 years 24 days ago
Enumerating and Ranking Discrete Motifs
Discrete motifsthat discriminate functionalclasses of proteins are useful for classifying newsequences, capturingstructural constraints, andidentifyingprotein subclasses.Despiteth...
Craig G. Nevill-Manning, Komal S. Sethi, Thomas D....
ISMB
1997
14 years 24 days ago
A Fast Heuristic Algorithm for a Probe Mapping Problem
Anewheuristic algorithm is presented for mapping probes to locations along the genome,given noisy pairwise distance data as input. Themodel consideredis quite general: Theinput co...
Brendan Mumey
ISMB
1997
14 years 24 days ago
Automatic Construction of Knowledge Base from Biological Papers
Yoshihiro Ohta, Yasunori Yamamoto, Tomoko Okazaki,...
ISMB
1997
14 years 24 days ago
Prediction of Enzyme Classification from Protein Sequence without the Use of Sequence Similarity
1 W’edescribe a novel approach for predicting the function of a protein from its amino-acid sequence. Given features that can be computedfrom the amino-acid sequence in a straigh...
Marie desJardins, Peter D. Karp, Markus Krummenack...
ISMB
1997
14 years 24 days ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg