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BMCBI
2010
150views more  BMCBI 2010»
13 years 11 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2010
176views more  BMCBI 2010»
13 years 11 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
BIODATAMINING
2008
140views more  BIODATAMINING 2008»
13 years 11 months ago
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics appr
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
BC
2008
68views more  BC 2008»
13 years 11 months ago
Neural control of Caenorhabditis elegans forward locomotion: the role of sensory feedback
Abstract This paper presents a simple yet biologicallygrounded model for the neural control of Caenorhabditis elegans forward locomotion. We identify a minimal circuit within the C...
John Bryden, Netta Cohen
BC
2008
134views more  BC 2008»
13 years 11 months ago
Interacting with an artificial partner: modeling the role of emotional aspects
In this paper we introduce a simple model based on probabilistic finite state automata to describe an emotional interaction between a robot and a human user, or between simulated a...
Isabella Cattinelli, Massimiliano Goldwurm, N. Alb...
BC
2008
38views more  BC 2008»
13 years 11 months ago
Spike-timing in primary sensory neurons: a model of somatosensory transduction in the rat
Abstract In previous work, we constructed a simple electromechanical model of transduction in the rat mystacial follicle that was able to replicate primary afferent response profil...
Benjamin Mitchinson, Ehsan Arabzadeh, Mathew E. Di...
BC
2007
62views more  BC 2007»
13 years 11 months ago
A quantitative synchronization model for smooth pursuit target tracking
We propose a quantitative model for human smooth pursuit tracking of a continuously moving visual target which is based on synchronization of an internal expectancy model of the ta...
Henning U. Voss, Bruce D. McCandliss, Jamshid Ghaj...
BC
2007
98views more  BC 2007»
13 years 11 months ago
Extending the mirror neuron system model, I
The paper introduces mirror neuron system II (MNS2), a new version of the MNS model (Oztop and Arbib in Biol Cybern 87(2):116–140, 2002) of action recognition learning by mirror ...
James Bonaiuto, Edina Rosta, Michael A. Arbib
AUTOMATICA
2008
139views more  AUTOMATICA 2008»
13 years 11 months ago
Structured low-rank approximation and its applications
Fitting data by a bounded complexity linear model is equivalent to low-rank approximation of a matrix constructed from the data. The data matrix being Hankel structured is equival...
Ivan Markovsky
AUTOMATICA
2008
74views more  AUTOMATICA 2008»
13 years 11 months ago
Krylov projection framework for Fourier model reduction
This paper analyzes the Fourier model reduction (FMR) method from a rational Krylov projection framework and shows how the FMR reduced model, which has guaranteed stability and a ...
Serkan Gugercin, Karen Willcox