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BMCBI
2008
108views more  BMCBI 2008»
14 years 21 days ago
Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
BMCBI
2008
135views more  BMCBI 2008»
14 years 21 days ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...