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BMCBI
2010
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13 years 11 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
ICARIS
2004
Springer
14 years 4 months ago
Definition of MHC Supertypes Through Clustering of MHC Peptide Binding Repertoires
MHC molecules, also known in the human as human leukocyte antigens (HLA), display peptides on antigen presenting cell surfaces for subsequent T cell recognition. Identification of ...
Pedro A. Reche, Ellis L. Reinherz