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JCC
2006
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13 years 11 months ago
A search algorithm for fixed-composition protein design
: We present a computational protein design algorithm for finding low-energy sequences of fixed amino acid composition. The search algorithms used in protein design typically do no...
Geoffrey K. Hom, Stephen L. Mayo
JCC
2008
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13 years 11 months ago
An improved pairwise decomposable finite-difference Poisson-Boltzmann method for computational protein design
Abstract: Our goal is to develop accurate electrostatic models that can be implemented in current computational protein design protocols. To this end, we improve upon a previously ...
Christina L. Vizcarra, Naigong Zhang, Shannon A. M...
BMCBI
2006
137views more  BMCBI 2006»
13 years 11 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...