BMCBI
2010
14 years 20 days ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BIOSYSTEMS
2008
14 years 20 days ago
2008
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
ISMB
1994
14 years 1 months ago
1994
Thispaperdescribesthe applicationof the Inductive Logic Programming0LP) program GOLEMto the discoveryof constraintsin the packingof beta-sheets in alpha/betaproteins. Theseconstra...
BIOCOMP
2008
14 years 2 months ago
2008
BIRD
2008
Springer
14 years 2 months ago
2008
Springer
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
BICOB
2010
Springer
14 years 5 months ago
2010
Springer
Molecular dynamics simulations have been employed by biologists to study the protein folding problem. Such simulations have resulted in a large number of protein folding trajector...
AI
2003
Springer
14 years 5 months ago
2003
Springer
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
ISNN
2004
Springer
14 years 6 months ago
2004
Springer
Abstract. Inter-residue contacts map prediction is one of the most important intermediate steps to the protein folding problem. In this paper, we focus on protein inter-residue con...
PPDP
2005
Springer
14 years 6 months ago
2005
Springer
The paper describes a constraint-based solution to the protein folding problem on face-centered cubic lattices—a biologically meaningful approximation of the general protein fol...
ISAAC
2005
Springer
14 years 6 months ago
2005
Springer
We introduce the concept of multi-directional width-bounded geometric separator and get improved separator for the grid graph, which improves exact algorithm for the protein foldin...