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NAR
2008
114views more  NAR 2008»
13 years 11 months ago
NetworKIN: a resource for exploring cellular phosphorylation networks
Protein kinases control cellular responses by phosphorylating specific substrates. Recent proteomewide mapping of protein phosphorylation sites by mass spectrometry has discovered...
Rune Linding, Lars Juhl Jensen, Adrian Pasculescu,...
BMCBI
2008
110views more  BMCBI 2008»
13 years 11 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
BMCBI
2010
97views more  BMCBI 2010»
13 years 11 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg