Recent studies (Alizadeh et al, [1]; Bittner et al,[5]; Golub et al, [11]) demonstrate the discovery of putative disease subtypes from gene expression data. The underlying computa...
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
A method is presented that uses b-strand interactions to predict the parallel right-handed b-helix super-secondary structural motif in protein sequences. A program called BetaWrap...
Phil Bradley, Lenore Cowen, Matthew Menke, Jonatha...
Phylogenetic footprinting is a comparative genomics approach for predicting transcription factor binding sites, where a set of orthologous regulatory regions are compared and short...