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BMCBI
2008
83views more  BMCBI 2008»
13 years 11 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
BIOWIRE
2007
Springer
14 years 5 months ago
Evolutionary and Temporal Dynamics of Transcriptional Regulatory Networks
Transcriptional regulation is a key mechanism that allows cells to make the appropriate amount of proteins at the right time. This is mediated by transcription factors that respond...
M. Madan Babu
AB
2007
Springer
14 years 5 months ago
Relating Attractors and Singular Steady States in the Logical Analysis of Bioregulatory Networks
Abstract. In 1973 R. Thomas introduced a logical approach to modeling and analysis of bioregulatory networks. Given a set of Boolean functions describing the regulatory interaction...
Heike Siebert, Alexander Bockmayr
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 6 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...