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    BIOCOMP
    2008
    93views Bioinformatics» more  BIOCOMP 2008»
    Discoveries in shRNA Design
    14 years 28 days ago
    Discoveries in shRNA Design
    Download  ww2.sjc.edu
    -- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
    Hong Zhou, Xiao Zeng, Joseph Manthey
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    BIBM
    2008
    IEEE
    105views Bioinformatics» more  BIBM 2008»
    Energy Profile and Secondary Structure Impact shRNA Efficacy
    14 years 6 months ago
    Energy Profile and Secondary Structure Impact shRNA Efficacy
    Download  www.sjc.edu
    Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...
    Hong Zhou, Xiao Zeng
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