signal peptides | Sciweavers

36

BMCBI
2005

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13 years 11 months ago

Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...

Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan

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17

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BMCBI
2008

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Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal p

13 years 11 months ago

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Background: Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated acr...

Khar Heng Choo, Joo Chuan Tong, Shoba Ranganathan

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29

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ISMB
1998

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Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model

14 years 24 days ago

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A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...

Henrik Nielsen, Anders Krogh

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