NAR
2006
14 years 3 months ago
2006
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
BMCBI
2006
14 years 3 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
BIRD
2008
Springer
2008
Springer
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
14 years 5 months ago
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...