TCBB
2010
13 years 6 months ago
2010
Cell membrane proteins play an important role in tissue architecture and cell-cell communication. We hypothesize that segmentation and multidimensional characterization of the dist...
TCBB
2010
13 years 10 months ago
2010
TCBB
2010
13 years 10 months ago
2010
—Proteins and their interactions govern virtually all cellular processes, such as regulation, signaling, metabolism, and structure. Most experimental findings pertaining to such ...
TCBB
2010
13 years 10 months ago
2010
We show that subtree prune and regraft (uSPR) distance on unrooted trees is fixed parameter tractable with respect to the distance. We also make progress on a conjecture of Steel...
TCBB
2010
13 years 10 months ago
2010
— We present efficient cache-oblivious algorithms for some well-studied string problems in bioinformatics including the longest common subsequence, global pairwise sequence alig...
TCBB
2010
13 years 10 months ago
2010
—Models of regulatory networks become more difficult to construct and understand as they grow in size and complexity. Large models are usually built up from smaller models, repre...
TCBB
2010
13 years 10 months ago
2010
—Phylogenetic networks are leaf-labeled, rooted, acyclic, directed graphs, that are used to model reticulate evolutionary histories. Several measures for quantifying the topologi...
TCBB
2010
13 years 10 months ago
2010
— We explore the maximum parsimony (MP) and ancestral maximum likelihood (AML) criteria in phylogenetic tree reconstruction. Both problems are NP hard, so we seek approximate sol...
TCBB
2010
13 years 10 months ago
2010
TCBB
2010
13 years 10 months ago
2010
—The literature on protein function prediction is currently dominated by works aimed at maximizing predictive accuracy, ignoring the important issues of validation and interpreta...