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WABI
2004
Springer
14 years 5 months ago
Chaining Algorithms for Alignment of Draft Sequence
Abstract. In this paper we propose a chaining method that can align a draft genomic sequence against a finished genome. We introduce the use of an overlap tree to enhance the state...
Mukund Sundararajan, Michael Brudno, Kerrin Small,...
WABI
2004
Springer
100views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Reversing Gene Erosion - Reconstructing Ancestral Bacterial Genomes from Gene-Content and Order Data
In the last few years, it has become routine to use gene-order data to reconstruct phylogenies, both in terms of edge distances (parsimonious sequences of operations that transform...
Joel V. Earnest-DeYoung, Emmanuelle Lerat, Bernard...
WABI
2004
Springer
132views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Joint Analysis of DNA Copy Numbers and Gene Expression Levels
Abstract. Genomic instabilities, amplifications, deletions and translocations are often observed in tumor cells. In the process of cancer pathogenesis cells acquire multiple genom...
Doron Lipson, Amir Ben-Dor, Elinor Dehan, Zohar Ya...
WABI
2004
Springer
14 years 5 months ago
Local Search Heuristic for Rigid Protein Docking
Abstract. We give an algorithm that locally improves the fit between two proteins modeled as space-filling diagrams. The algorithm defines the fit in purely geometric terms and...
Vicky Choi, Pankaj K. Agarwal, Herbert Edelsbrunne...
WABI
2004
Springer
107views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Phylogenetic Super-networks from Partial Trees
—In practice, one is often faced with incomplete phylogenetic data, such as a collection of partial trees or partial splits. This paper poses the problem of inferring a phylogene...
Daniel H. Huson, Tobias Dezulian, Tobias H. Kl&oum...
WABI
2004
Springer
116views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Topological Rearrangements and Local Search Method for Tandem Duplication Trees
—The problem of reconstructing the duplication history of a set of tandemly repeated sequences was first introduced by Fitch [4]. Many recent studies deal with this problem, show...
Denis Bertrand, Olivier Gascuel
WABI
2004
Springer
142views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Linear Reduction for Haplotype Inference
Abstract. Haplotype inference problem asks for a set of haplotypes explaining a given set of genotypes. Popular software tools for haplotype inference (e.g., PHASE, HAPLOTYPER) as ...
Jingwu He, Alexander Zelikovsky
WABI
2004
Springer
14 years 5 months ago
Reconstructing Ancestral Gene Orders Using Conserved Intervals
Conserved intervals were recently introduced as a measure of similarity between genomes whose genes have been shuffled during evolution by genomic rearrangements. Phylogenetic reco...
Anne Bergeron, Mathieu Blanchette, Annie Chateau, ...
WABI
2004
Springer
109views Bioinformatics» more  WABI 2004»
14 years 5 months ago
Online Consensus and Agreement of Phylogenetic Trees
Computational heuristics are the primary methods for reconstruction of phylogenetic trees on large datasets. Most large-scale phylogenetic analyses produce numerous trees that are ...
Tanya Y. Berger-Wolf