Abstract. In this paper we propose a chaining method that can align a draft genomic sequence against a finished genome. We introduce the use of an overlap tree to enhance the state...
Mukund Sundararajan, Michael Brudno, Kerrin Small,...
In the last few years, it has become routine to use gene-order data to reconstruct phylogenies, both in terms of edge distances (parsimonious sequences of operations that transform...
Joel V. Earnest-DeYoung, Emmanuelle Lerat, Bernard...
Abstract. Genomic instabilities, amplifications, deletions and translocations are often observed in tumor cells. In the process of cancer pathogenesis cells acquire multiple genom...
Doron Lipson, Amir Ben-Dor, Elinor Dehan, Zohar Ya...
Abstract. We give an algorithm that locally improves the fit between two proteins modeled as space-filling diagrams. The algorithm defines the fit in purely geometric terms and...
Vicky Choi, Pankaj K. Agarwal, Herbert Edelsbrunne...
—In practice, one is often faced with incomplete phylogenetic data, such as a collection of partial trees or partial splits. This paper poses the problem of inferring a phylogene...
Daniel H. Huson, Tobias Dezulian, Tobias H. Kl&oum...
—The problem of reconstructing the duplication history of a set of tandemly repeated sequences was first introduced by Fitch [4]. Many recent studies deal with this problem, show...
Abstract. Haplotype inference problem asks for a set of haplotypes explaining a given set of genotypes. Popular software tools for haplotype inference (e.g., PHASE, HAPLOTYPER) as ...
Conserved intervals were recently introduced as a measure of similarity between genomes whose genes have been shuffled during evolution by genomic rearrangements. Phylogenetic reco...
Anne Bergeron, Mathieu Blanchette, Annie Chateau, ...
Computational heuristics are the primary methods for reconstruction of phylogenetic trees on large datasets. Most large-scale phylogenetic analyses produce numerous trees that are ...