Abstract. With Next Generation Sequencers, sequence based transcriptomic or epigenomic assays yield millions of short sequence reads that need to be mapped back on a reference geno...
Eric Rivals, Leena Salmela, Petteri Kiiskinen, Pet...
Abstract. Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present e...
Background: Supertree methods combine the phylogenetic information from multiple partially-overlapping trees into a larger phylogenetic tree called a supertree. Several supertree ...
We develop, analyze and experiment with a new tool, called madmx, which extracts frequent motifs, possibly including don’t care characters, from biological sequences. We introduc...
Roberto Grossi, Andrea Pietracaprina, Nadia Pisant...
Abstract. The existing synteny block reconstruction algorithms use anchors (e.g., orthologous genes) shared over all genomes to construct the synteny blocks for multiple genomes. T...
Qian Peng, Max A. Alekseyev, Glenn Tesler, Pavel A...
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
We present a novel dynamic programming framework that allows one to compute tight upper bounds for the p-values of gapped local alignments in pseudo–polynomial time. Our algorith...