Error Tolerance of DNA Self-Assembly by Monomer Concentration Control

Abstract— This paper proposes the control of monomer concentration as a novel improvement of the kinetic Tile Assembly Model (kTAM) to reduce the error rate in DNA selfassembly. Tolerance to errors in this process is very important for manufacturing highly dense ICs; the proposed technique significantly decreases error rates (i.e. it increases error tolerance) by controlling the concentration of monomers. A stochastic analysis based on a new state model is presented. Error rates reductions of at least 10% are found by evaluating the proposed scheme comparing to a scheme with constant concentration. One of the significant advantages of the proposed scheme is that it doesn’t entail an overhead such as increase in size and a slow growth, while still achieving a significant reduction in error rate.

• Type: Conference
• Year: 2006
• Where: DFT
• Authors: Byunghyun Jang, Yong-Bin Kim, Fabrizio Lombardi
• Keywords: DFT 2006, Error Rate, Error Rates Reductions, Error Tolerance, Hardware