In this paper, we propose a lexicon-driven and ontologymerging methodology of constructing diachronic domain knowledge via Sinica BOW, a bilingual ontological lexical resource based on WordNet and SUMO ontology. The main domain knowledge that we model our specialized ontology on is GuangQunFangPu,a Chinese classic literature of botany. Our studies yields promising result, we believe that the proposed research scenario will boost the on-going development of e-Humanities.