Abstract— In this paper, we propose a new MIMO-HSDPA transmission scheme with two transmit and two receive antennas, using an optimal Space-Time block code: the Golden code [1]. This code has a full rate, a full diversity, achieves the Diversity-Multiplexing gain tradeoff and preserves the mutual information. The proposed scheme is compared to the RCMPD [2] a scheme which has also a full rate and a full diversity. The major disadvantage of the later is the generation of the Multiple Access Interference (MAI) even on a flat fading channel. Simulation results show that the proposed scheme has better performances specially for high spectral efficiency. The RCMPD performance are hardly affected by the MAI.