Clinical decision-making involves an active interplay between various medical knowledge modalities—the spectrum of medical knowledge modalities spanning from tacit knowledge to experiential knowledge to explicit knowledge to data-induced knowledge. The ability to simultaneously access and then integrate multiple knowledge modalities pertaining to a common clinical theme is profound for clinical decision making. In this concept paper we introduce knowledge morphing—a knowledge modeling task that allows the integration of heterogeneous medical knowledge modalities, with respect to a clinical case, to yield a comprehensive knowledge resource for decision-support.