Patterns of Gene Deletion following Genome Duplication in Yeast

Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following WGD in yeast with simulations. We find that deletion events alternate between paralogous chromosomes more often than expected under a random duplicate deletion model.

• Type: Conference
• Year: 2005
• Where: CSB
• Authors: Jake K. Byrnes, Wen-Hsiung Li
• Keywords: Bioinformatics, CSB 2005, Duplicate Deletion, Massive Duplicate Deletion, Random Duplicate Deletion