Real-Time Treatment Planning Optimisation for Brachytherapy

In this paper, we present an integrated system for real-time dose distribution calculation and treatment planning optimisation for brachytherapy of prostate cancer, with a special emphasis on the visual integration of the dosimetry and target images obtained from the open magnetic resonance system. This system involves a fast method to calculate dose distributions of multiple concurrent radioactive sources, based on the combination of elements from a database of pre-calculated dose distribution maps for single sources, combined linearly to provide the final dose distribution map. Simulated annealing, in conjunction with the inverse planning method, is used to determine the source dwell times at pre-selected locations in order to optimally irradiate the tumour while preserving the surrounding healthy tissues. This algorithm, implemented in FORTRAN, is integrated into a computer-assisted treatment planning tool, written in JAVA, using the runtime class and RMI API of Java. The whole sys...

• Type: Conference
• Year: 2005
• Where: DFMA
• Authors: Simon Chatelain, Jean-Philippe Thiran, Valery-Olivier Zilio, Marc-Olivier Bettler, O. P. Joneja, Rakesh Chawla, Youri Popowski
• Keywords: DFMA 2005, Dose Distribution, Dose Distribution Calculation, Dose Distribution Map, Multimedia