We perform a detailed study of various crosstalk scenarios in VDSM technologies by using a distributed model of the crosstalk site and make a number of key observations about the crosstalk effects in VLSI circuits. As example of these observations, we report that the combination of one crosstalk event at some site and another crosstalk event at a different site in the transitive fan-out of the first site may cause a slowdown or speedup of the circuit by an amount that can significantly exceed the sum of crosstalk effects caused by each site in isolation. As another example, we report that the common assumption that zero skew between the input transitions of aggressor and victim lines causes the worst case crosstalk effect is not always valid, and therefore, optimization or test based on such an assumption may be invalid. We also demonstrate the non-monotone behavior of the crosstalk effect with respect to the skew between the input transition of aggressor and victim lines. This work p...