Suitable programming models and associated supporting infrastructures are required to deal with large software systems dived in complex and dynamic network environments. Here, with the aid of a case study scenario, we discuss the inadequacies of current approaches in dealing with such scenarios. Then we sketch the key characteristics of TOTA (Tuples On The Air), as a novel proposal to deal with the above inadequacies. TOTA relies on tuple-based information to be spatially diffused in the network and to be exploited by application agents so as to achieve contextawareness and consequently to effectively coordinate with each other despite the network dynamics.