Contribution to Gene Expression Data Analysis by Means of Set Pattern Mining

Abstract. One of the exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, it is extremely useful to provide putative synexpression groups or transcription modules to molecular biologists. We propose a methodology that has been proved useful in real cases. It is described as a prototypical KDD scenario which starts from raw expression data selection until useful patterns are delivered. It has been validated on real data sets. Our conceptual contribution is (a) to emphasize how to take the most from recent progress in constraint-based mining of set patterns, and (b) to propose a generic approach for gene expression data enrichment. Doing so, we survey our algorithmic breakthrough which has been the core of our contribution to the IST FET cInQ project.

• Type: Conference
• Year: 2004
• Where: CINQ
• Authors: Ruggero G. Pensa, Jérémy Besson, Céline Robardet, Jean-François Boulicaut
• Keywords: CINQ 2004, Database, Expression Data, Expression Data Selection, Gene Expression Data