Healthcare organizations exhibit both detailed and dynamic complexity. Effective and sustainable decisionmaking in healthcare requires tools that can comprehend this complexity. Discrete event simulation (DES) due to its ability to capture detail complexity is widely used for operational decision making. However at the strategic level, System Dynamics (SD) with its focus on a holistic perspective and its ability to comprehend dynamic complexity has advantages over DES. Appreciating the complexity of healthcare, the authors have proposed the use of hybrid simulation in healthcare. As argued previously, effective decision making require tools which are capable of comprehending both detail and dynamic interactions of healthcare. The interactions in the organizations are governed by the governance design. In appreciation of that argument the authors have described the applicability of a hybrid approach to various modes of governance in UK healthcare.